Morris water maze animal experiment

MORRIS water maze animals experiments are a swimming of forced experimental animals (rats, mice), learning to look for hidden An experiment of the water platform, Morris water maze is mainly used to test the learning memory capability of experimental animals to spatial position and direction (space positioning), is widely used in learning memory, elderly dementia, hippocampus / external seahorse research, intelligence Sepament, new drug development / screening / evaluation, pharmacology, toxicology, preventive medicine, neuronics, animal psychology and behavioral biology, etc., have been widely recognized It is a classic experiment of studying behaviors in medical institutions, especially learning and memory research.

u0026 oslash; Standardized industrial design, hardware is beautiful and durable

u0026 oslash; no need to dye the experimental animal, software automatic tracking

[ 123] u0026 oslash; Unique dynamic background recognition algorithm, effectively identified anti-interference and accuracy

u0026 OSLASH; support tracking identification of multiple experimental animals, enhance experimental efficiency Accuracy

u0026 OSLASH; Users can set each other's independent experiment data archive folder for experimental materials (including storage video and data) management

u0026 oslash; Humanization of software interface, detail, indicator function is rich

u0026 oslash; adopt video camera tracking technology, realizing the automation of the experiment process, avoiding Subjective errors introduced by artificial counts and interference to experimental animals u0026 nbsp, increase the authenticity and reliability of the experimental results. u0026 OSLASH; Perfect Experiment Control Function , you can transfer experimental projects at any time to continue experimental and data to view and export operations. After the experiment, you can immediately view the data of the experiment, playback recording, and trajectory can be output to the standard bitmap file, and the data can be output to the Excel file, which is convenient for analysis.

u0026 OSLASH; unique event logger, track the software operation of the experiment at any time, automatically prompt, Easy to maintain

Morris water maze animals

experiment

123]

* quadrant

residence time , Activity distance, number of enters, incubation, average speed (X-axis projection speed)

residence time, activity distance, Number of enters, incubation, average speed (X-axis projection speed)

The third quadrant

residence time, activity distance, number of enters, latency , Average speed (X-axis projection speed)

Fourth quadrant

residence time, activity distance, access, incubation, average speed ( X-axis projection speed)

Station

Enter (cross) number, latency

Ring, Central, Peripheral

Experimental Method

Training Step

Optical training

(1) Put the animal (rat Or mouse) The head is placed in the pool wall, placed in the position of the East, West, South, and Northern Starting position. Record the time (s) of the underwater platform (s). In the previous training, if this time exceeds 60s, the animals are guided to the platform. Let the animals stay 10s on the platform. (2) remove the animals and dry. Animals (especially rat) were placed under 150W incandescent lamps to bake 5 min and put it back into the cage. Each animal training 4 times a day, between 15 to 20 minutes between two training, and continuous training 5D.

Probe Training [123

The next day after the end of acquiring training, the platform was removed and the 60s exploration training was started. The animal is placed in water from the opposite side of the original platform quadrant. Record the time spent on the target quadrant (the quadrant of the platform originally placed) and the number of times the quadrant is entered, in this regard as the detection indicator of space memory.

Memory (Working Memory) was measured. The second day after the exploration training is over, starting to maintain 4 days of opposition training. Place the platform in the pair side quadrant of the quadrant in the original platform, the method is the same as obtained. Train 4 times a day. Each time you record the time and swimming distance of the platform and swimming speed.

The second day of the latter pair training is performed on the second day of the latter training training

. The method is similar to the above-mentioned exploration training. Recording the number of times the animal 60s internal animals in the target quadrant (the platform is located) and the number of times the area is entered.

Test is a forced experimental animal (rat, mouse) Swimming, learning to find an experiment hidden in the platform, Morris water maze is mainly used to test the learning memory capability of experimental animals to spatial position and direction (space positioning), is widely used in learning memory, old age dementia, hippocampus / Subject, intelligence and aging, new drug development / screening / evaluation, pharmacology, toxicology, preventive medicine, neurogenic, animal psychology and behavioral biology, etc. It has been widely recognized, and it is a classic experiment of studying behavior in medical institutions, especially learning and memory research.

u0026 OSLASH; standardized industrial design, Hardware is beautiful and durable u0026 OSLASH; no need to dye the experimental animal, software automatic tracking

u0026 OSLASH; unique dynamic background identification Algorithm, effectively identified anti-interference and accuracy

u0026 OSLASH; support tracking identifies multiple experimental animals, enhances experimental efficiency and accuracy

u0026 oslash; Users can set up an independent experimental data archive folder for each other to facilitate experimental materials (including storage video and data) Manage

u0026 OSLASH; software interface is humanized, operational instructions detail, indicator function is rich

u0026 OSLASH; use video camera tracking Technology, the automation of the experimental process is realized, avoiding the subjective error introduced by artificial count and interference to experimental animals increases the authenticity and reliability of the experimental results.

u0026 OSLASH; Perfect Experiment Control Function , you can transfer experimental projects at any time to continue experimental and data to view and export operations. After the experiment, you can immediately view the data of the experiment, playback recording, and trajectory can be output to the standard bitmap file, and the data can be output to the Excel file, which is convenient for analysis.

u0026 OSLASH; unique event logger, tracking the software operation of the experiment at any time, automatic prompt for remote maintenance

[123 ] Analysis index

indicator

[ 123]

Time, active distance, number of enters, incubation, average speed (X-axis projection speed)

Second quadrant

Sometimes, activity distance, number of enters, incubation, average speed (X-axis projection speed)

Third quadrant [ 123]

Sometimes, activity distance, number of enters, incubation, average speed (X-axis projection speed)

Fourth quadrant [123 ]

Residence time, activity distance, number of enters, incubation, average speed (X-axis projection speed)

Station

[123 ] Enter (cross) number, latency

residence time, activity distance, number of enters, incubation, average Speed u200b u200b(X-axis projection speed)

experimental method [123 ]

acquired training [123

(1) Put the animal (rat or mouse) head toward the pool wall into the water, place one of the four starting positions randomly taking the east, west, south, north. Record the time (s) of the underwater platform (s). In the previous training, if this time exceeds 60s, the animals are guided to the platform. Let the animals stay 10s on the platform. (2) remove the animals and dry. Animals (especially rat) were placed under 150W incandescent lamps to bake 5 min and put it back into the cage. Each animal training 4 times a day, between 15 to 20 minutes between two training, and continuous training 5D.

The second day after the end of the acquisition training, the platform was removed, and the 60s exploration training was started. The animal is placed in water from the opposite side of the original platform quadrant. Record the time spent on the target quadrant (the quadrant of the platform originally placed) and the number of times the quadrant is entered, in this regard as the detection indicator of space memory.

The second day of the latter pair training is performed on the second day of the latter training training

u0026 OSLASH; standardized industrial design, Hardware is beautiful and durable

u0026 OSLASH; no need to dye the experimental animal, software automatic tracking

u0026 OSLASH; unique dynamic background identification Algorithm, effectively identified anti-interference and accuracy

u0026 OSLASH; support tracking identifies multiple experimental animals, enhances experimental efficiency and accuracy

u0026 oslash; Users can set each other's independent experimental data archive folder for experimental materials (including storage video and data) management

u0026 OSLASH; software interface is humanized , The operation instruction details, the indicator function is rich u0026 oslash; use video camera tracking technology to automate the experimental process, avoid subjective errors introduced by artificial counts and experimental animals u0026 nbsp The interference increases the authenticity and reliability of the experimental results.

u0026 OSLASH; unique event logger, tracking the software operation of the experiment at any time, automatic prompt for remote maintenance

[123 ] Analysis index

indicator [ 123]

Time, active distance, number of enters, incubation, average speed (X-axis projection speed)

Second quadrant

Sometimes, activity distance, number of enters, incubation, average speed (X-axis projection speed)

Third quadrant [ 123]

Residence time, activity distance, number of enters, incubation, average speed (X-axis projection speed)

Fourth quadrant

residence time , Activity distance, number of enters, incubation, average speed (X-axis projection speed)

Enter (cross) times, latency [ 123]

Inner ring, Central, Peripheral

residence time, active distance, number of enters, incubation, average speed (X-axis projection speed) [123

Experimental Method

Optical training [123

(1) Put the animal (rat or mouse) toward the wall into the water, place one of the four starting positions randomly taking the east, west, south, north. Record the time (s) of the underwater platform (s). In the previous training, if this time exceeds 60s, the animals are guided to the platform. Let the animals stay 10s on the platform.

(2) remove the animals and dry. Animals (especially rat) were placed under 150W incandescent lamps to bake 5 min and put it back into the cage. Each animal training 4 times a day, between 15 to 20 minutes between two training, and continuous training 5D.

Typographic exploration training

The first alignment trainingTwo days.The method is similar to the above-mentioned exploration training.Recording the number of times the animal 60s internal animals in the target quadrant (the platform is located) and the number of times the area is entered.

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